Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach

We present a data-driven mathematical model of a key initiating step in platelet activation, a central process in the prevention of bleeding following Injury. In vascular disease, this process is activated inappropriately and causes thrombosis, heart attacks and stroke. The collagen receptor GPVI is...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunster, Joanne L., Mazet, Francoise, Fry, Michael J., Gibbins, Jonathan M., Tindall, Marcus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652868/
https://www.ncbi.nlm.nih.gov/pubmed/26584182
http://dx.doi.org/10.1371/journal.pcbi.1004589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652868/
https://www.ncbi.nlm.nih.gov/pubmed/26584182
http://dx.doi.org/10.1371/journal.pcbi.1004589

Ejemplares similares