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Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach

We present a data-driven mathematical model of a key initiating step in platelet activation, a central process in the prevention of bleeding following Injury. In vascular disease, this process is activated inappropriately and causes thrombosis, heart attacks and stroke. The collagen receptor GPVI is...

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Detalles Bibliográficos
Autores principales:	Dunster, Joanne L., Mazet, Francoise, Fry, Michael J., Gibbins, Jonathan M., Tindall, Marcus J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652868/ https://www.ncbi.nlm.nih.gov/pubmed/26584182 http://dx.doi.org/10.1371/journal.pcbi.1004589

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