In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma

Glioblastoma (GBM) is the most lethal brain cancer with profound genomic alterations. While the bona fide tumor suppressor genes such as PTEN, NF1, and TP53 have high frequency of inactivating mutations, there may be the genes with GBM-suppressive roles for which genomic mutation is not a primary ca...

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Detalles Bibliográficos
Autores principales: Sa, Jason K., Yoon, Yeup, Kim, Misuk, Kim, Yeonghwan, Cho, Hee Jin, Lee, Jin-Ku, Kim, Gi-Soo, Han, Suji, Kim, Woon Jin, Shin, Yong Jae, Joo, Kyeung Min, Paddison, Patrick J., Ishitani, Tohru, Lee, Jeongwu, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652994/
https://www.ncbi.nlm.nih.gov/pubmed/26023737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652994/
https://www.ncbi.nlm.nih.gov/pubmed/26023737

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