Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR

The mutation of T790M in EGFR is a major mechanism of resistance to treatment with EGFR-TKIs. Only qualitative detection (presence or absence) of T790M has been described to date, however. Digital PCR (dPCR) analysis has recently been applied to the quantitative detection of target molecules in canc...

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Detalles Bibliográficos
Autores principales: Iwama, Eiji, Takayama, Koichi, Harada, Taishi, Okamoto, Isamu, Ookubo, Fumihiko, Kishimoto, Junji, Baba, Eishi, Oda, Yoshinao, Nakanishi, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653018/
https://www.ncbi.nlm.nih.gov/pubmed/26015401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653018/
https://www.ncbi.nlm.nih.gov/pubmed/26015401

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