Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cutaneous T-cell lymphoma (CTCL). However, it remains only partially understood how Jak3/STAT activati...

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Detalles Bibliográficos
Autores principales: Sibbesen, Nina A., Kopp, Katharina L., Litvinov, Ivan V., Jønson, Lars, Willerslev-Olsen, Andreas, Fredholm, Simon, Petersen, David L., Nastasi, Claudia, Krejsgaard, Thorbjørn, Lindahl, Lise M., Gniadecki, Robert, Mongan, Nigel P., Sasseville, Denis, Wasik, Mariusz A., Iversen, Lars, Bonefeld, Charlotte M., Geisler, Carsten, Woetmann, Anders, Odum, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653025/
https://www.ncbi.nlm.nih.gov/pubmed/26244872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653025/
https://www.ncbi.nlm.nih.gov/pubmed/26244872

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