Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents

Cancer cells are characterized by a high dependency on antioxidant enzymes to cope with the elevated rates of reactive oxygen species (ROS). Impairing antioxidant capacity in cancer cells disturbs the ROS homeostasis and exposes cancer cells to massive oxidative stress. In this study, we have discov...

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Detalles Bibliográficos
Autores principales: Lin, Chenchu, Zeng, Hanlin, Lu, Junyan, Xie, Zuoquan, Sun, Wenyi, Luo, Cheng, Ding, Jian, Yuan, Shengtao, Geng, Meiyu, Huang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653027/
https://www.ncbi.nlm.nih.gov/pubmed/26008972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653027/
https://www.ncbi.nlm.nih.gov/pubmed/26008972

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