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Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents
Cancer cells are characterized by a high dependency on antioxidant enzymes to cope with the elevated rates of reactive oxygen species (ROS). Impairing antioxidant capacity in cancer cells disturbs the ROS homeostasis and exposes cancer cells to massive oxidative stress. In this study, we have discov...
Autores principales: | Lin, Chenchu, Zeng, Hanlin, Lu, Junyan, Xie, Zuoquan, Sun, Wenyi, Luo, Cheng, Ding, Jian, Yuan, Shengtao, Geng, Meiyu, Huang, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653027/ https://www.ncbi.nlm.nih.gov/pubmed/26008972 |
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