Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer

T-cell exhaustion represents a progressive loss of T-cell function. The inhibitory receptor PD-1 is known to negatively regulate CD8(+) T cell responses directed against tumor antigen, but the blockades of PD-1 pathway didn't show the objective responses in patients with colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales: Xu, Benling, Yuan, Long, Gao, Quanli, Yuan, Peng, Zhao, Peng, Yuan, Huijuan, Fan, Huijie, Li, Tiepeng, Qin, Peng, Han, Lu, Fang, Weijia, Suo, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653028/
https://www.ncbi.nlm.nih.gov/pubmed/26008981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653028/
https://www.ncbi.nlm.nih.gov/pubmed/26008981

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