The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

Lysophosphatidic acid (LPA) is a bioactive lipid promoting cancer metastasis. LPA activates a series of six G protein-coupled receptors (LPA(1-6)). While blockage of LPA(1) in vivo inhibits breast carcinoma metastasis, down-stream genes mediating LPA-induced metastasis have not been yet identified....

Descripción completa

Detalles Bibliográficos
Autores principales: Sahay, Debashish, Leblanc, Raphael, Grunewald, Thomas G. P., Ambatipudi, Srikant, Ribeiro, Johnny, Clézardin, Philippe, Peyruchaud, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653029/
https://www.ncbi.nlm.nih.gov/pubmed/26098771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653029/
https://www.ncbi.nlm.nih.gov/pubmed/26098771

Ejemplares similares