A versatile transgenic allele for mouse overexpression studies

For the analysis of gene function in vivo, gene overexpression in the mouse provides an alternative to loss-of-function knock-out approaches and can help reveal phenotypes where compensatory mechanisms are at play. Furthermore, when multiple lines overexpressing a gene-of-interest at varying levels...

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Detalles Bibliográficos
Autores principales: Dolatshad, Hamid, Biggs, Daniel, Diaz, Rebeca, Hortin, Nicole, Preece, Christopher, Davies, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653235/
https://www.ncbi.nlm.nih.gov/pubmed/26369329
http://dx.doi.org/10.1007/s00335-015-9602-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653235/
https://www.ncbi.nlm.nih.gov/pubmed/26369329
http://dx.doi.org/10.1007/s00335-015-9602-y

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