A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA)

Motivation: We address the following question: Does inhibition of the expression of a gene X in a cellular assay affect the expression of another gene Y? Rather than inhibiting gene X experimentally, we aim at answering this question computationally using as the only input observational gene express...

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Detalles Bibliográficos
Autores principales: Taruttis, Franziska, Spang, Rainer, Engelmann, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653390/
https://www.ncbi.nlm.nih.gov/pubmed/26249813
http://dx.doi.org/10.1093/bioinformatics/btv461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653390/
https://www.ncbi.nlm.nih.gov/pubmed/26249813
http://dx.doi.org/10.1093/bioinformatics/btv461

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