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A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA)
Motivation: We address the following question: Does inhibition of the expression of a gene X in a cellular assay affect the expression of another gene Y? Rather than inhibiting gene X experimentally, we aim at answering this question computationally using as the only input observational gene express...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653390/ https://www.ncbi.nlm.nih.gov/pubmed/26249813 http://dx.doi.org/10.1093/bioinformatics/btv461 |