Identification and functional characterization of rare SHANK2 variants in schizophrenia

Recent genetic data on schizophrenia (SCZ) have suggested that proteins of the postsynaptic density of excitatory synapses have a role in its etiology. Mutations in the three SHANK genes encoding for postsynaptic scaffolding proteins have been shown to represent risk factors for autism spectrum diso...

Descripción completa

Detalles Bibliográficos
Autores principales: Peykov, S, Berkel, S, Schoen, M, Weiss, K, Degenhardt, F, Strohmaier, J, Weiss, B, Proepper, C, Schratt, G, Nöthen, M M, Boeckers, T M, Rietschel, M, Rappold, G A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653611/
https://www.ncbi.nlm.nih.gov/pubmed/25560758
http://dx.doi.org/10.1038/mp.2014.172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653611/
https://www.ncbi.nlm.nih.gov/pubmed/25560758
http://dx.doi.org/10.1038/mp.2014.172

Ejemplares similares