The human decapping scavenger enzyme DcpS modulates microRNA turnover

The decapping scavenger enzyme DcpS is known for its role in hydrolyzing the cap structure following mRNA degradation. Recently, we discovered a new function in miRNA degradation activation for the ortholog of DcpS in C. elegans. Here we show that human DcpS conserves its role in miRNA turnover. In...

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Detalles Bibliográficos
Autores principales: Meziane, Oussama, Piquet, Sandra, Bossé, Gabriel D., Gagné, Dominic, Paquet, Eric, Robert, Claude, Tones, Michael A., Simard, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653633/
https://www.ncbi.nlm.nih.gov/pubmed/26584588
http://dx.doi.org/10.1038/srep16688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653633/
https://www.ncbi.nlm.nih.gov/pubmed/26584588
http://dx.doi.org/10.1038/srep16688

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