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Changes in poly(A) tail length dynamics from the loss of the circadian deadenylase Nocturnin

mRNA poly(A) tails are important for mRNA stability and translation, and enzymes that regulate the poly(A) tail length significantly impact protein profiles. There are eleven putative deadenylases in mammals, and it is thought that each targets specific transcripts, although this has not been clearl...

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Detalles Bibliográficos
Autores principales: Kojima, Shihoko, Gendreau, Kerry L., Sher-Chen, Elaine L., Gao, Peng, Green, Carla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653638/
https://www.ncbi.nlm.nih.gov/pubmed/26586468
http://dx.doi.org/10.1038/srep17059