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Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation

Spermatogonial stem cells (SSCs) have significant applications in both reproductive and regenerative medicine. However, primary human SSCs are very rare, and a human SSC line has not yet been available. In this study, we have for the first time reported a stable human SSC line by stably expressing h...

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Detalles Bibliográficos
Autores principales: Hou, Jingmei, Niu, Minghui, Liu, Linhong, Zhu, Zijue, Wang, Xiaobo, Sun, Min, Yuan, Qingqing, Yang, Shi, Zeng, Wenxian, Liu, Yang, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653657/
https://www.ncbi.nlm.nih.gov/pubmed/26585066
http://dx.doi.org/10.1038/srep16922