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Annotation inconsistencies beyond sequence similarity-based function prediction – phylogeny and genome structure

The function annotation process in computational biology has increasingly shifted from the traditional characterization of individual biochemical roles of protein molecules to the system-wide detection of entire metabolic pathways and genomic structures. The so-called genome-aware methods broaden mi...

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Detalles Bibliográficos
Autores principales: Promponas, Vasilis J., Iliopoulos, Ioannis, Ouzounis, Christos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653902/
https://www.ncbi.nlm.nih.gov/pubmed/26594309
http://dx.doi.org/10.1186/s40793-015-0101-2