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Annotation inconsistencies beyond sequence similarity-based function prediction – phylogeny and genome structure
The function annotation process in computational biology has increasingly shifted from the traditional characterization of individual biochemical roles of protein molecules to the system-wide detection of entire metabolic pathways and genomic structures. The so-called genome-aware methods broaden mi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653902/ https://www.ncbi.nlm.nih.gov/pubmed/26594309 http://dx.doi.org/10.1186/s40793-015-0101-2 |