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Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor β signal activation and liver regeneration after hepatectomy in an experimental model

BACKGROUND: A strategy for accelerating liver regeneration after hepatectomy would offer great benefits in preventing postoperative liver failure and improving surgical outcomes. Transforming growth factor (TGF) β is a potent inhibitor of hepatocyte proliferation. Recently, thrombospondin (TSP) 1 ha...

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Detalles Bibliográficos
Autores principales: Kuroki, H, Hayashi, H, Nakagawa, S, Sakamoto, K, Higashi, T, Nitta, H, Hashimoto, D, Chikamoto, A, Beppu, T, Baba, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654236/
https://www.ncbi.nlm.nih.gov/pubmed/25866938
http://dx.doi.org/10.1002/bjs.9765