Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers

Faithful DNA replication is vital to prevent disease-causing mutations, chromosomal aberrations and malignant transformation. However, accuracy conflicts with pace and flexibility and cells rely on specialized polymerases and helicases to ensure effective and timely replication of genomes that conta...

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Detalles Bibliográficos
Autores principales: Lemmens, Bennie, van Schendel, Robin, Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654259/
https://www.ncbi.nlm.nih.gov/pubmed/26563448
http://dx.doi.org/10.1038/ncomms9909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654259/
https://www.ncbi.nlm.nih.gov/pubmed/26563448
http://dx.doi.org/10.1038/ncomms9909

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