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Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers
Faithful DNA replication is vital to prevent disease-causing mutations, chromosomal aberrations and malignant transformation. However, accuracy conflicts with pace and flexibility and cells rely on specialized polymerases and helicases to ensure effective and timely replication of genomes that conta...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Pub. Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654259/ https://www.ncbi.nlm.nih.gov/pubmed/26563448 http://dx.doi.org/10.1038/ncomms9909 |