Cargando…

MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions

Although the genetic basis of mitral valve prolapse (MVP) has now been clearly established, the molecular and cellular mechanisms involved in the pathological processes associated to a specific mutation often remain to be determined. The FLNA gene (encoding Filamin A; FlnA) was the first gene associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Duval, Damien, Labbé, Pauline, Bureau, Léa, Le Tourneau, Thierry, Norris, Russell A., Markwald, Roger R., Levine, Robert, Schott, Jean-Jacques, Mérot, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654411/
https://www.ncbi.nlm.nih.gov/pubmed/26594644
http://dx.doi.org/10.3390/jcdd2030233