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Questioned validity of Gene Expression Dysregulated Domains in Down's Syndrome

Recently, in studies examining fibroblasts obtained from the tissues of one set of monozygotic twins (i.e. fetuses derived from the same egg) discordant for trisomy 21 (Down syndrome; DS), Letourneau et al., ( )reported the presence of a defined pattern of dysregulation within specific genomic domai...

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Detalles Bibliográficos
Autores principales: Do, Long H., Mobley, William C., Singhal, Nishant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654439/
https://www.ncbi.nlm.nih.gov/pubmed/26664707
http://dx.doi.org/10.12688/f1000research.6735.1