RabGEF1/Rabex-5 Regulates TrkA-Mediated Neurite Outgrowth and NMDA-Induced Signaling Activation in NGF-Differentiated PC12 Cells

Nerve growth factor (NGF) binds to its cognate receptor TrkA and induces neuronal differentiation by activating distinct downstream signal transduction events. RabGEF1 (also known as Rabex-5) is a guanine nucleotide exchange factor for Rab5, which regulates early endosome fusion and vesicular traffi...

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Detalles Bibliográficos
Autores principales: Tam, See-Ying, Lilla, Jennifer N., Chen, Ching-Cheng, Kalesnikoff, Janet, Tsai, Mindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654474/
https://www.ncbi.nlm.nih.gov/pubmed/26588713
http://dx.doi.org/10.1371/journal.pone.0142935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654474/
https://www.ncbi.nlm.nih.gov/pubmed/26588713
http://dx.doi.org/10.1371/journal.pone.0142935

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