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Stochastic Regulation of her1/7 Gene Expression Is the Source of Noise in the Zebrafish Somite Clock Counteracted by Notch Signalling

The somite segmentation clock is a robust oscillator used to generate regularly-sized segments during early vertebrate embryogenesis. It has been proposed that the clocks of neighbouring cells are synchronised via inter-cellular Notch signalling, in order to overcome the effects of noisy gene expres...

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Detalles Bibliográficos
Autores principales: Jenkins, Robert P., Hanisch, Anja, Soza-Ried, Cristian, Sahai, Erik, Lewis, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654481/
https://www.ncbi.nlm.nih.gov/pubmed/26588097
http://dx.doi.org/10.1371/journal.pcbi.1004459