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Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid

Treg cells play a crucial role in immune tolerance, but mechanisms that induce Treg cells are poorly understood. We here have described eosinophils in lamina propria (LP) that displayed high aldehyde dehydrogenase (ALDH) activity, a rate-limiting step during all-trans retinoic acid (ATRA) synthesis,...

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Detalles Bibliográficos
Autores principales: Chen, Hong-Hu, Sun, Ai-Hua, Ojcius, David M., Hu, Wei-Lin, Ge, Yu-Mei, Lin, Xu’ai, Li, Lan-Juan, Pan, Jian-Ping, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654556/
https://www.ncbi.nlm.nih.gov/pubmed/26587591
http://dx.doi.org/10.1371/journal.pone.0142881