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Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid
Treg cells play a crucial role in immune tolerance, but mechanisms that induce Treg cells are poorly understood. We here have described eosinophils in lamina propria (LP) that displayed high aldehyde dehydrogenase (ALDH) activity, a rate-limiting step during all-trans retinoic acid (ATRA) synthesis,...
Autores principales: | Chen, Hong-Hu, Sun, Ai-Hua, Ojcius, David M., Hu, Wei-Lin, Ge, Yu-Mei, Lin, Xu’ai, Li, Lan-Juan, Pan, Jian-Ping, Yan, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654556/ https://www.ncbi.nlm.nih.gov/pubmed/26587591 http://dx.doi.org/10.1371/journal.pone.0142881 |
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