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The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production
The hepatitis C virus (HCV) p7 protein is required for infectious virus production via its role in assembly and ion channel activity. Although NMR structures of p7 have been reported, the location of secondary structural elements and orientation of the p7 transmembrane domains differ among models. F...
Autores principales: | Scull, Margaret A., Schneider, William M., Flatley, Brenna R., Hayden, Robert, Fung, Canny, Jones, Christopher T., van de Belt, Marieke, Penin, François, Rice, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654572/ https://www.ncbi.nlm.nih.gov/pubmed/26588073 http://dx.doi.org/10.1371/journal.ppat.1005297 |
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