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Direct Detection of Unnatural DNA Nucleotides dNaM and d5SICS using the MspA Nanopore

Malyshev et al. showed that the four-letter genetic code within a living organism could be expanded to include the unnatural DNA bases dNaM and d5SICS. However, verification and detection of these unnatural bases in DNA requires new sequencing techniques. Here we provide proof of concept detection o...

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Detalles Bibliográficos
Autores principales: Craig, Jonathan M., Laszlo, Andrew H., Derrington, Ian M., Ross, Brian C., Brinkerhoff, Henry, Nova, Ian C., Doering, Kenji, Tickman, Benjamin I., Svet, Mark T., Gundlach, Jens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654578/
https://www.ncbi.nlm.nih.gov/pubmed/26588074
http://dx.doi.org/10.1371/journal.pone.0143253