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Direct Detection of Unnatural DNA Nucleotides dNaM and d5SICS using the MspA Nanopore
Malyshev et al. showed that the four-letter genetic code within a living organism could be expanded to include the unnatural DNA bases dNaM and d5SICS. However, verification and detection of these unnatural bases in DNA requires new sequencing techniques. Here we provide proof of concept detection o...
Autores principales: | Craig, Jonathan M., Laszlo, Andrew H., Derrington, Ian M., Ross, Brian C., Brinkerhoff, Henry, Nova, Ian C., Doering, Kenji, Tickman, Benjamin I., Svet, Mark T., Gundlach, Jens H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654578/ https://www.ncbi.nlm.nih.gov/pubmed/26588074 http://dx.doi.org/10.1371/journal.pone.0143253 |
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