Cargando…

X-ray structure of the mammalian GIRK2 – βγ G protein complex

G protein-gated inward rectifier K(+) (GIRK) channels allow neurotransmitters, via G protein-coupled receptor stimulation, to control cellular electrical excitability. In cardiac and neuronal cells this control regulates heart rate and neural circuit activity. We present the 3.5 Å resolution crystal...

Descripción completa

Detalles Bibliográficos
Autores principales: Whorton, Matthew R., MacKinnon, Roderick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654628/
https://www.ncbi.nlm.nih.gov/pubmed/23739333
http://dx.doi.org/10.1038/nature12241