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X-ray structure of the mammalian GIRK2 – βγ G protein complex
G protein-gated inward rectifier K(+) (GIRK) channels allow neurotransmitters, via G protein-coupled receptor stimulation, to control cellular electrical excitability. In cardiac and neuronal cells this control regulates heart rate and neural circuit activity. We present the 3.5 Å resolution crystal...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654628/ https://www.ncbi.nlm.nih.gov/pubmed/23739333 http://dx.doi.org/10.1038/nature12241 |