Rapid Detection Method for the Four Most Common CHEK2 Mutations Based on Melting Profile Analysis

INTRODUCTION: CHEK2 is a tumor suppressor gene, and the mutations affecting the functionality of the protein product increase cancer risk in various organs. The elevated risk, in a significant percentage of cases, is determined by the occurrence of one of the four most common mutations in the CHEK2...

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Detalles Bibliográficos
Autores principales: Borun, Pawel, Salanowski, Kacper, Godlewski, Dariusz, Walkowiak, Jaroslaw, Plawski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654745/
https://www.ncbi.nlm.nih.gov/pubmed/26446916
http://dx.doi.org/10.1007/s40291-015-0171-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654745/
https://www.ncbi.nlm.nih.gov/pubmed/26446916
http://dx.doi.org/10.1007/s40291-015-0171-2

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