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Rapid Detection Method for the Four Most Common CHEK2 Mutations Based on Melting Profile Analysis
INTRODUCTION: CHEK2 is a tumor suppressor gene, and the mutations affecting the functionality of the protein product increase cancer risk in various organs. The elevated risk, in a significant percentage of cases, is determined by the occurrence of one of the four most common mutations in the CHEK2...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654745/ https://www.ncbi.nlm.nih.gov/pubmed/26446916 http://dx.doi.org/10.1007/s40291-015-0171-2 |