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A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels

BACKGROUND: A deeper understanding of differences and similarities in transcriptional regulation between species can uncover important information about gene functions and the role of genes in disease. Deciphering such patterns between mice and humans is especially important since mice play an essen...

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Detalles Bibliográficos
Autores principales: Monaco, Gianni, van Dam, Sipko, Casal Novo Ribeiro, João Luis, Larbi, Anis, de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654840/
https://www.ncbi.nlm.nih.gov/pubmed/26589719
http://dx.doi.org/10.1186/s12862-015-0534-7