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Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

BACKGROUND: L-methionine, the principal sulfur-containing amino acid in proteins, plays critical roles in cell physiology as an antioxidant and in the breakdown of fats and heavy metals. Previous studies suggesting the use of L-methionine as a treatment for depression and other diseases indicate tha...

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Detalles Bibliográficos
Autores principales: Tapia-Rojas, Cheril, Lindsay, Carolina B., Montecinos-Oliva, Carla, Arrazola, Macarena S., Retamales, Rocio M., Bunout, Daniel, Hirsch, Sandra, Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654847/
https://www.ncbi.nlm.nih.gov/pubmed/26590557
http://dx.doi.org/10.1186/s13024-015-0057-0