Matrix-derived inflammatory mediator N-acetyl proline-glycine-proline is neurotoxic and upregulated in brain after ischemic stroke

BACKGROUND: N-acetyl proline-glycine-proline (ac-PGP) is a matrix-derived chemokine produced through the proteolytic destruction of collagen by matrix metalloproteinases (MMPs). While upregulation and activation of MMPs and concomitant degradation of the extracellular matrix are known to be associat...

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Detalles Bibliográficos
Autores principales: Hill, Jeff W., Nemoto, Edwin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654865/
https://www.ncbi.nlm.nih.gov/pubmed/26588897
http://dx.doi.org/10.1186/s12974-015-0428-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654865/
https://www.ncbi.nlm.nih.gov/pubmed/26588897
http://dx.doi.org/10.1186/s12974-015-0428-z

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