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Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

BACKGROUND: Disrupted bile secretion leads to liver damage characterized by inflammation, fibrosis, eventually cirrhosis, and hepatocellular cancer. As obstructive cholestasis often progresses insidiously, markers for the diagnosis and staging of the disease are urgently needed. To this end, we comp...

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Detalles Bibliográficos
Autores principales: Abshagen, Kerstin, König, Matthias, Hoppe, Andreas, Müller, Isabell, Ebert, Matthias, Weng, Honglei, Holzhütter, Herrmann-Georg, Zanger, Ulrich M., Bode, Johannes, Vollmar, Brigitte, Thomas, Maria, Dooley, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654904/
https://www.ncbi.nlm.nih.gov/pubmed/26589287
http://dx.doi.org/10.1186/s12918-015-0229-0