Cargando…

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

BACKGROUND: Disrupted bile secretion leads to liver damage characterized by inflammation, fibrosis, eventually cirrhosis, and hepatocellular cancer. As obstructive cholestasis often progresses insidiously, markers for the diagnosis and staging of the disease are urgently needed. To this end, we comp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abshagen, Kerstin, König, Matthias, Hoppe, Andreas, Müller, Isabell, Ebert, Matthias, Weng, Honglei, Holzhütter, Herrmann-Georg, Zanger, Ulrich M., Bode, Johannes, Vollmar, Brigitte, Thomas, Maria, Dooley, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654904/ https://www.ncbi.nlm.nih.gov/pubmed/26589287 http://dx.doi.org/10.1186/s12918-015-0229-0

Ejemplares similares

The protective effect of allopurinol on cholestatic liver injury induced by bile duct ligation.
por: Mun, K. C., et al.
Publicado: (1996)

Shenqi Fuzheng Injection impairs bile duct ligation-induced cholestatic liver injury in vivo
por: Cao, Fei, et al.
Publicado: (2019)

Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct–Ligated Mouse
por: Cai, Shi-Ying, et al.
Publicado: (2019)

18β-Glycyrrhetinic Acid Protects against Cholestatic Liver Injury in Bile Duct-Ligated Rats
por: Pan, Pin-Ho, et al.
Publicado: (2022)

Peripheral and spinal 5-HT receptors participate in cholestatic itch and antinociception induced by bile duct ligation in rats
por: Tian, Bin, et al.
Publicado: (2016)

Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice
por: Kennedy, Lindsey, et al.
Publicado: (2016)

The Role of Gut Microbiota in Mice With Bile Duct Ligation-Evoked Cholestatic Liver Disease-Related Cognitive Dysfunction
por: Yang, Bowen, et al.
Publicado: (2022)

Mechanism of Paeoniflorin in the Treatment of Bile Duct Ligation-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology
por: Wei, Shizhang, et al.
Publicado: (2020)

Positive Effects of Ger-Gen-Chyn-Lian-Tang on Cholestatic Liver Fibrosis in Bile Duct Ligation-Challenged Mice
por: Chang, Zi-Yu, et al.
Publicado: (2019)

Treatment of the Fluoroquinolone-Associated Disability: The Pathobiochemical Implications
por: Michalak, Krzysztof, et al.
Publicado: (2017)

Smouldering Lesion in MS: Microglia, Lymphocytes and Pathobiochemical Mechanisms
por: Pukoli, Dániel, et al.
Publicado: (2023)

Metabolomic Assessment of Acute Cholestatic Injuries Induced by Thioacetamide and by Bile Duct Ligation, and the Protective Effects of Huang-Lian-Jie-Du-Decoction
por: Wei, Dan-Dan, et al.
Publicado: (2018)

Comb Atrophy after Bile Duct Ligation in Chickens
por: Yoshioka, Kazuki, et al.
Publicado: (2018)

Induction of Rat Liver Alkaline Phosphatase by Bile Duct Ligation
por: Kaplan, Marshall M.
Publicado: (1979)

THE EFFECT OF LIGATION OF THE COMMON BILE DUCT ON CHOLESTEROL SYNTHESIS IN THE RAT
por: Fredrickson, Donald S., et al.
Publicado: (1954)

Time course of collagen peak in bile duct-ligated rats
por: Tarcin, Orhan, et al.
Publicado: (2011)

Pathobiochemical Changes in Diabetic Skeletal Muscle as Revealed by Mass-Spectrometry-Based Proteomics
por: Ohlendieck, Kay
Publicado: (2012)

New pathobiochemical insights into dystrophinopathy from the proteomics of senescent mdx mouse muscle
por: Holland, Ashling, et al.
Publicado: (2014)

The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia–Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats
por: Iwasaki, Junji, et al.
Publicado: (2019)

Anti-inflammatory consequences of bile acid accumulation in virus-infected bile duct ligated mice
por: Rattay, Stephanie, et al.
Publicado: (2018)

Non-invasive biomarkers for identification of vanishing bile duct syndrome among children with acute cholestatic hepatitis
por: Wang, Neng-Li, et al.
Publicado: (2023)

Impairment of the Organization of Locomotor and Exploratory Behaviors in Bile Duct-Ligated Rats
por: Leke, Renata, et al.
Publicado: (2012)

Pathophysiology of Lung Injury Induced by Common Bile Duct Ligation in Mice
por: Shikata, Fumiaki, et al.
Publicado: (2014)

Melatonin Alleviates Liver Apoptosis in Bile Duct Ligation Young Rats
por: Sheen, Jiunn-Ming, et al.
Publicado: (2016)

Protective effect of dehydroandrographolide on obstructive cholestasis in bile duct-ligated mice
por: Weng, Zhiyong, et al.
Publicado: (2017)

Carvedilol Attenuates the Progression of Hepatic Fibrosis Induced by Bile Duct Ligation
por: Tian, Xiaopeng, et al.
Publicado: (2017)

Transcriptome Profile of Thyroid Glands in Bile Duct Ligation Mouse Model
por: Jo, Danbi, et al.
Publicado: (2022)

n-3 PUFAs reduce tumor load and improve survival in a NASH-tumor mouse model
por: Liebig, Marie, et al.
Publicado: (2019)

Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2(−/−) mice by modulating composition, signalling and excretion of faecal bile acids
por: Fuchs, Claudia Daniela, et al.
Publicado: (2018)

Effect of Bile Pigments on the Compromised Gut Barrier Function in a Rat Model of Bile Duct Ligation
por: Zhou, Kangkang, et al.
Publicado: (2014)

β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor
por: Klag, Thomas, et al.
Publicado: (2018)

Simultaneous bile duct and portal vein ligation induces faster atrophy/hypertrophy complex than portal vein ligation: role of bile acids
por: Ren, Weizheng, et al.
Publicado: (2015)

A novel murine model of reversible bile duct obstruction demonstrates rapid improvement of cholestatic liver injury
por: Taylor, Sarah A., et al.
Publicado: (2020)

Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2(−/−) mouse model of sclerosing cholangitis via immunomodulatory effects
por: Fuchs, Claudia D., et al.
Publicado: (2022)

Yes-Associated Protein Regulates the Hepatic Response After Bile Duct Ligation
por: Bai, Haibo, et al.
Publicado: (2012)

Cholestasis progression effects on long-term memory in bile duct ligation rats
por: Hosseini, Nasrin, et al.
Publicado: (2014)

Lactobacillus Aggravate Bile Duct Ligation-Induced Liver Inflammation and Fibrosis in Mice
por: Roh, Yoon Seok, et al.
Publicado: (2018)

Cholestasis induced by bile duct ligation promotes changes in the intestinal microbiome in mice
por: Cabrera-Rubio, Raul, et al.
Publicado: (2019)

Effects of erythropoietin on bile duct ligation-induced neuro-inflammation in male rats
por: Golshani, Moazameh, et al.
Publicado: (2019)

Efficiency of Hesperidin against Liver Fibrosis Induced by Bile Duct Ligation in Rats
por: Nasehi, Zahra, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_28pcn5hfqao21kmma93md3kuvd