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Optimal experimental designs for dose–response studies with continuous endpoints

In most areas of clinical and preclinical research, the required sample size determines the costs and effort for any project, and thus, optimizing sample size is of primary importance. An experimental design of dose–response studies is determined by the number and choice of dose levels as well as th...

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Detalles Bibliográficos
Autores principales: Holland-Letz, Tim, Kopp-Schneider, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655015/
https://www.ncbi.nlm.nih.gov/pubmed/25155192
http://dx.doi.org/10.1007/s00204-014-1335-2