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Optimal experimental designs for dose–response studies with continuous endpoints
In most areas of clinical and preclinical research, the required sample size determines the costs and effort for any project, and thus, optimizing sample size is of primary importance. An experimental design of dose–response studies is determined by the number and choice of dose levels as well as th...
Autores principales: | Holland-Letz, Tim, Kopp-Schneider, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655015/ https://www.ncbi.nlm.nih.gov/pubmed/25155192 http://dx.doi.org/10.1007/s00204-014-1335-2 |
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