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Genetic Variations in ABCG2 Gene Predict Breast Carcinoma Susceptibility and Clinical Outcomes after Treatment with Anthracycline-Based Chemotherapy

The genetic variants of the ATP-binding cassette, subfamily G, member 2 (ABCG2) are known to be involved in developing cancer risk and interindividual differences in chemotherapeutic response. The polymorphisms in ABCG2 gene were genotyped by using PCR-RFLP assays. We found that ABCG2 G34A GA/AA gen...

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Detalles Bibliográficos
Autores principales: Wu, Huizhe, Liu, Yong, Kang, Hui, Xiao, Qinghuan, Yao, Weifan, Zhao, Haishan, Wang, Enhua, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655035/
https://www.ncbi.nlm.nih.gov/pubmed/26634205
http://dx.doi.org/10.1155/2015/279109