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RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation

Cancer cells acquire invasive ability to degrade and adhere to extracellular matrix (ECM) and migrate to adjacent tissues. This ultimately results metastasis. Hence, the present study investigated the in vitro effects of cyclopeptide glycoside, RA-XII on cell adhesion, invasion, proliferation and ma...

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Detalles Bibliográficos
Autores principales: Leung, Hoi-Wing, Zhao, Si-Meng, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Fung, Kwok-Pui, Leung, Ping-Chung, Tan, Ning-Hua, Lau, Clara Bik-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655310/
https://www.ncbi.nlm.nih.gov/pubmed/26592552
http://dx.doi.org/10.1038/srep16985