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RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation
Cancer cells acquire invasive ability to degrade and adhere to extracellular matrix (ECM) and migrate to adjacent tissues. This ultimately results metastasis. Hence, the present study investigated the in vitro effects of cyclopeptide glycoside, RA-XII on cell adhesion, invasion, proliferation and ma...
Autores principales: | Leung, Hoi-Wing, Zhao, Si-Meng, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Fung, Kwok-Pui, Leung, Ping-Chung, Tan, Ning-Hua, Lau, Clara Bik-San |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655310/ https://www.ncbi.nlm.nih.gov/pubmed/26592552 http://dx.doi.org/10.1038/srep16985 |
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