Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes

Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within...

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Detalles Bibliográficos
Autores principales: Lam, Tze Hau, Tay, Matthew Zirui, Wang, Bei, Xiao, Ziwei, Ren, Ee Chee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655331/
https://www.ncbi.nlm.nih.gov/pubmed/26593880
http://dx.doi.org/10.1038/srep16972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655331/
https://www.ncbi.nlm.nih.gov/pubmed/26593880
http://dx.doi.org/10.1038/srep16972

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