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Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain
Failure to close the neural tube results in birth defects, with severity ranging from spina bifida to lethal anencephaly. Few genetic risk factors for neural tube defects are known in humans, highlighting the critical role of environmental risk factors, such as maternal diabetes. Yet, it is not well...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655353/ https://www.ncbi.nlm.nih.gov/pubmed/26593875 http://dx.doi.org/10.1038/srep16917 |