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Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain

Failure to close the neural tube results in birth defects, with severity ranging from spina bifida to lethal anencephaly. Few genetic risk factors for neural tube defects are known in humans, highlighting the critical role of environmental risk factors, such as maternal diabetes. Yet, it is not well...

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Detalles Bibliográficos
Autores principales: Salbaum, J. Michael, Kruger, Claudia, MacGowan, Jacalyn, Herion, Nils J., Burk, David, Kappen, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655353/
https://www.ncbi.nlm.nih.gov/pubmed/26593875
http://dx.doi.org/10.1038/srep16917