Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice

Obesity is a chronic condition resulting from a long-term pattern of poor diet and lifestyle. Long-term consumption of high-fat diet (HFD) leads to persistent activation and leptin resistance in AgRP neurons in the arcuate nucleus of the hypothalamus (ARH). Here, for the first time, we demonstrate a...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Pham, Kevin, Gammons, Jesse W., Sutherland, Daniel, Liu, Yanyun, Smith, Alana, Kaczorowski, Catherine C., O’Connell, Kristen M.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655371/
https://www.ncbi.nlm.nih.gov/pubmed/26592769
http://dx.doi.org/10.1038/srep16810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655371/
https://www.ncbi.nlm.nih.gov/pubmed/26592769
http://dx.doi.org/10.1038/srep16810

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