Direct uptake of Antagomirs and efficient knockdown of miRNA in primary B and T lymphocytes

Depending on their physiological expression level, microRNAs (miRNA) address different target genes, thus have different biological functions. To identify these, the physiological expression has to be blocked. Here, we describe the use of inhibitory cholesterol-modified oligonucleotides (Antagomirs)...

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Detalles Bibliográficos
Autores principales: Haftmann, Claudia, Riedel, René, Porstner, Martina, Wittmann, Jürgen, Chang, Hyun-Dong, Radbruch, Andreas, Mashreghi, Mir-Farzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655414/
https://www.ncbi.nlm.nih.gov/pubmed/26187895
http://dx.doi.org/10.1016/j.jim.2015.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655414/
https://www.ncbi.nlm.nih.gov/pubmed/26187895
http://dx.doi.org/10.1016/j.jim.2015.07.006

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