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Direct uptake of Antagomirs and efficient knockdown of miRNA in primary B and T lymphocytes
Depending on their physiological expression level, microRNAs (miRNA) address different target genes, thus have different biological functions. To identify these, the physiological expression has to be blocked. Here, we describe the use of inhibitory cholesterol-modified oligonucleotides (Antagomirs)...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655414/ https://www.ncbi.nlm.nih.gov/pubmed/26187895 http://dx.doi.org/10.1016/j.jim.2015.07.006 |