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Self-assembled amyloid fibrils with controllable conformational heterogeneity

Amyloid fibrils are a hallmark of neurodegenerative diseases and exhibit a conformational diversity that governs their pathological functions. Despite recent findings concerning the pathological role of their conformational diversity, the way in which the heterogeneous conformations of amyloid fibri...

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Detalles Bibliográficos
Autores principales: Lee, Gyudo, Lee, Wonseok, Lee, Hyungbeen, Lee, Chang Young, Eom, Kilho, Kwon, Taeyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655422/
https://www.ncbi.nlm.nih.gov/pubmed/26592772
http://dx.doi.org/10.1038/srep16220