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Polymerase δ replicates both strands after homologous recombination-dependent fork restart

To maintain genetic stability DNA must be replicated only once and replication completed even when individual replication forks are inactivated. Because fork inactivation is common, the passive convergence of an adjacent fork is insufficient to rescue all inactive forks. Thus, eukaryotic cells have...

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Detalles Bibliográficos
Autores principales: Miyabe, Izumi, Mizuno, Ken’Ichi, Keszthelyi, Andrea, Daigaku, Yasukazu, Skouteri, Meliti, Mohebi, Saed, Kunkel, Thomas A., Murray, Johanne M., Carr, Antony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655445/
https://www.ncbi.nlm.nih.gov/pubmed/26436826
http://dx.doi.org/10.1038/nsmb.3100