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Polymerase δ replicates both strands after homologous recombination-dependent fork restart
To maintain genetic stability DNA must be replicated only once and replication completed even when individual replication forks are inactivated. Because fork inactivation is common, the passive convergence of an adjacent fork is insufficient to rescue all inactive forks. Thus, eukaryotic cells have...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655445/ https://www.ncbi.nlm.nih.gov/pubmed/26436826 http://dx.doi.org/10.1038/nsmb.3100 |